BMT CTN 0701: A Phase II Trial of Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation for Patients with Relapsed Follicular Non-Hodgkin's Lymphoma Beyond First Complete Response

Study Status

Open to Enrollment

Study Description

Blood stem cell transplants are one treatment option for people with lymphoma or other types of blood cancers. For this type of treatment, family members or unrelated donors with a similar tissue type usually donate their blood stem cells to the transplant patients. This study will evaluate the effectiveness of a type of blood stem cell transplant that uses lower doses of chemotherapy in people with relapsed follicular non-Hodgkin's lymphoma (NHL).

Typically, people who are undergoing a blood stem cell transplant receive high doses of chemotherapy before the transplant to prepare their bodies to accept the donor stem cells. In this study, participants will undergo a type of stem cell transplant called a nonmyeloablative transplant, which involves a reduced intensity method of transplantation that does not require high doses of chemotherapy. The purpose of this study is to examine the effectiveness of a nonmyeloablative allogeneic blood stem cell transplant at improving survival rates in people with relapsed follicular non-Hodgkin's lymphoma (NHL).

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Disease Status and/or Stage

Relapsed Follicular Non-Hodgkin's Lymphoma

Sponsor

National Heart, Lung and Blood Institute (NHLBI); National Cancer Institute

Key Eligibility

  • Relapsed follicular non-Hodgkin's lymphoma
  • Any number of prior regimens; the most recent prior regimen must have occurred more than 28 days before entering the study
  • Detailed eligibility discussed when you contact the study team

Principal Investigator

Tsiporah Shore, MD

Contact

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Contact Us

For general inquiries, or if you need assistance finding a study, please contact:

Robert Hagerty
Subject Recruitment Manager
Tel: (646) 962-9340
roh2026@med.cornell.edu

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