Solid Tumor

Show Only Open Trials
4.

REO 017: A Phase 2 Study of Reolysin® in Combination with Gemcitabine for Patients with Advanced Pancreatic Adenocarcinoma

  • Study Status: Open to Enrollment
  • Disease Status and/or Stage: Advanced or Metastatic Pancreatic Cancer
5.

A Randomized, Blinded, Phase 2 Dose-Ranging Study of BMS-936558 (MDX-1106) in Subjects with Progressive Advanced/Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy

  • Study Status: Closed to Enrollment
  • Sponsor: Bristol-Myers Squibb
  • Disease Status and/or Stage: Advanced/Metastatic Renal Cell Carcinoma (RCC)
6.

A Phase II Study of Tetrathiomolybdate (TM) in patients with breast cancer at moderate to high risk of recurrence

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: High-Risk Stage II Breast Cancer; Stage III Breast Cancer; Stage IV Breast Cancer in Remission
7.

S0221: Phase III Trial of Continuous Schedule AC + G Vs. Q 2 Week Schedule AC, Followed by Paclitaxel Given Either Every 2 Weeks or Weekly for 12 Weeks as Post-Operative Adjuvant Therapy in Node-Positive or High-Risk Node Negative Breast Cancer

  • Study Status: Closed to Enrollment
  • Sponsor: SouthWest Oncology Group (SWOG) and The Cancer Support Trials Unit (CTSU)
  • Disease Status and/or Stage: Operable Stage 1, II or II Invasive Breast Cancer
8.

Prospective Data Collection Among Women Using Cold Caps During TC Chemotherapy

  • Study Status: Open to Enrollment
  • Disease Status and/or Stage: Early-Stage Breast Cancer
10.

A Phase 1b Safety Study of Abiraterone Acetate (JNJ 212082) and Docetaxel in Subjects with Metastatic Castration-Resistant Prostate Cancer (mCRPC) (COU-AA-206)

  • Study Status: Open to Enrollment
  • Sponsor: Cougar Biotechnology
  • Disease Status and/or Stage: Metastatic Castration-Resistant Prostate Cancer
12.

A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients with High-Risk, Clinically Localized Prostate Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Cancer and Leukemia Group B, National Cancer Institute
  • Disease Status and/or Stage: High Risk, Clinically Localized Prostate Cancer
14.

A Phase 2 Trial of 177Lu Radiolabeled Monoclonal Antibody HuJ591-GS (177Lu-J591) in Patients with Metastatic Androgen-Independent Prostate Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Metastatic, Hormone-Refractory Prostate Cancer
16.

A Phase I Trial of Docetaxel/Prednisone plus Fractionated 177Lu-J591 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody in Patients with Metastatic, Castrate-Resistant Prostate Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Metastatic Prostate Cancer
17.

A Phase III trial of short term androgen deprivation with pelvic lymph node or prostate bed only radiotherapy (SPPORT) in prostate cancer patients with a rising PSA after radical prostatectomy

  • Study Status: Open to Enrollment
  • Sponsor: Radiation Therapy Oncology Group, National Cancer Institute
  • Disease Status and/or Stage: Prostate Cancer After Radical Prostatectomy
18.

A Phase 1B, Open-Label, Dose Escalation Study Evaluating the Safety of BSI-201 in Combination with Chemotherapeutic Regimens in Subjects with Advanced Solid Tumors

  • Study Status: Closed to Enrollment
  • Sponsor: BiPar Sciences
  • Disease Status and/or Stage: Metastatic Pancreatic Cancer
19.

A Phase Ib Study of Fractionated 90Y-hPAM4 Plus Gemcitabine in Patients With Previously Untreated Advanced Pancreatic Cancer.

  • Study Status: Closed to Enrollment
  • Sponsor: Immunomedics, Inc.
  • Disease Status and/or Stage: Untreated Advanced Pancreatic Cancer
22.

A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 2 Study of the Efficacy and Safety of Apricoxib in Combination with either Docetaxel or Pemetrexed in Non-Small Cell Lung Cancer Patients

  • Study Status: Open to Enrollment
  • Sponsor: Tragara Pharmaceuticals
  • Disease Status and/or Stage: Stage IIIB/IV or Recurrent, Unresectable Non-Small Cell Lung Cancer
23.

Chemotherapy and Radiation in Treating Patients With Stage 3 Non-Small Cell Lung Cancer (PROCLAIM)

  • Study Status: Open to Enrollment
  • Sponsor: Eli Lily & Co.
  • Disease Status and/or Stage: Unresectable, Locally Advance, Stage III Non-Small Cell Lung Cancer
24.

A Phase I/II Study of Vorinostat in Combination with Isotretinoin in the Treatment of Patients with Advanced Renal Cell Carcinoma

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College, National Cancer Institute
  • Disease Status and/or Stage: Metastatic or Advanced Kidney Cancer
25.

A Phase I/II Trial of BAY 43-9006 plus Gemcitabine and Capecitabine in the Treatment of Patients with Advanced Renal Cell Carcinoma

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College, National Cancer Institute
  • Disease Status and/or Stage: Advanced, Unresectable and/or Metastatic Kidney Cancer
26.

ECOG 2805: A Randomized, Double-Blind Phase III Trial of Adjuvant Sunitinib versus Sorafenib versus Placebo in Patients with Resected Renal Cell Carcinoma (RCC)

  • Study Status: Closed to Enrollment
  • Sponsor: Eastern Cooperative Oncology Group
  • Disease Status and/or Stage: Renal Cell Cancer
27.

A Phase II Trial of Temsirolimus and Bevacizumab in Patients With Endometrial, Ovarian, Hepatocellular Carcinoma, Carcinoid and Islet Cell Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Mayo Clinic, National Cancer Institute
  • Disease Status and/or Stage: Locally Advanced, Recurrant or Metastatic disease
28.

A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients With Advanced Transitional Cell Carcinoma

  • Study Status: Open to Enrollment
  • Sponsor: Cancer and Leukemia Group B (CALGB); National Cancer Institute (NCI)
  • Disease Status and/or Stage: Advanced Transitional Cell Carcinoma
29.

A Phase I Study of 177Lu Radiolabeled Monoclonal Antibody HuJ591-GS (177Lu-591) in Patients with Nonprostate Metastatic Solid Tumors: A Pilot Study

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College
  • Disease Status and/or Stage: Metastatic Solid Tumor
30.

A Phase I/II, Open-Label, Dose Escalation Study of CDX-1401 in Patients with Malignances Known to Express NY-ESO-1

  • Study Status: Closed to Enrollment
  • Sponsor: Celldex Therapeutics
  • Disease Status and/or Stage: Progressive Disease after therapies with curative potential or approved salvage regimen
31.
32.

E5103: A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer

  • Study Status: Open to Enrollment
  • Sponsor: Eastern Cooperative Oncology Group; National Cancer Institute
  • Disease Status and/or Stage: Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer
33.

A Phase I-II Study of R115777 (Tipifarnib, Zarnestraâ) Plus Sequential Weekly Paclitaxel followed by Dose-Dense Doxorubicin and Cyclophosphamide in Patients with Stage IIB-IIIC Breast Cancer

  • Study Status: Open to Enrollment
  • Sponsor: New York Cancer Consortium; National Cancer Institute
  • Disease Status and/or Stage: Stage IIB-IIC Breast Cancer
34.

Phase II study of ixabepilone in patients with metastatic breast cancer and a prospective evaluation of its effects on the ultrastructure of neurons

  • Study Status: Open to Enrollment
  • Sponsor: Weill Cornell Medical College; Bristol-Myers Squibb
  • Disease Status and/or Stage: Metastatic Breast Cancer
35.

ACOSOG Z1072: A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma

  • Study Status: Open to Enrollment
  • Sponsor: American College of Surgeons/National Cancer Institute
  • Disease Status and/or Stage: Invasive Breast Cancer
36.

A Phase II, Single-Arm, Multi-Center Study Evaluating the Combination of Vinorelbine and Lapatinib in Women with ErbB2 Overexpressing Metastatic Breast Cancer

  • Study Status: Closed to Enrollment
  • Sponsor: GlaxoSmithKline
  • Disease Status and/or Stage: Metastatic Breast Cancer
37.

Tinzaparin for Primary Treatment and Extended Secondary Prophylaxis of Venous Thromboembolism (VTE) in Patients with Cancer

  • Study Status: Closed to Enrollment
  • Disease Status and/or Stage: Any Stage of Cancer
39.

A Phase II Study of Tetrathiomolydate (TM) in patients with breast cancer at moderate to high risk for recurrence

  • Study Status: Open to Enrollment
  • Disease Status and/or Stage: Breast Cancer at moderate to high risk of recurrence (based on the number of lymph nodes); Stage 4 breast cancer without any evidence of disease

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